日本无限资源_福禄影院午夜伦_美国av毛片_亚洲自拍在线观看_激情亚洲一区国产精品_999久久久久

Israeli-U.S. research finds brain cancer cells change states

Source: Xinhua| 2019-09-24 01:34:10|Editor: yan
Video PlayerClose

JERUSALEM, Sept. 23 (Xinhua) -- Israeli and U.S. researchers found that glioblastoma brain cancer cells come in four states and can transition from one state to another, the Weizmann Institute of Science (WIS) in central Israel reported on Monday.

The study, published in the journal Cell, was led by researchers from WIS, Massachusetts General Hospital (MGH) in Boston and the Salk Institute for Biological Studies in La Jolla, California.

The findings might point to ways of developing future therapies to the incurable glioblastoma.

Glioblastoma tumors differ from one patient to the next, and even cells within each tumor differed greatly from one another.

According to the researchers, it is possible that no therapy has yet worked well because each drug kills only a subset of the tumor cells, and a successful future therapy will need to attack all four states.

The research team resorted to advanced technology called single-cell RNA sequencing, which provides information about gene expression in individual cells.

The team obtained tumor samples from 28 glioblastoma patients and created profiles of gene expression in some 24,000 tumor cells.

Using unique algorithms, they were able to correlate gene expression patterns with cell division and other normal and aberrant cellular activities.

This analysis enabled the scientists to identify four different cell subtypes, each characterized by its own gene activation program.

It was found that cancer cells hijack gene activation programs of developing cells, and these programs drive the growth of the tumors.

Then, the scientists "barcoded" glioblastoma cells into mice and tracked them over time, demonstrating that tumor cells do indeed transition between different cellular states.

In another experiment, they implanted human glioblastoma cells into mice, seeing that the cells later changed their identity.

The precise glioblastoma characterization points the way toward targeting future therapies against all tumor subtypes, after determining how each subtype responds to drugs.

The findings can also be applied to characterize the subtypes that occur in other cancers.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011105521384160121
主站蜘蛛池模板: 狠狠色丁香婷婷久久综合 | 91精品国产高清一区二区性色 | 精品国产人免费观看成人片 | 色噜噜色狠狠 | 福利视频10000 | 成熟女人毛片www免费版在线 | 久久国产午夜精品理论片34页 | 久久国产青偷人人妻潘金莲 | 91亚洲精品在线观看 | 国产专区一区 | 国产一起色一起爱 | 亚洲欧美日韩精品久久亚洲区色播 | 欧美亚洲日本国产黑白配 | 中文字幕人成无码免费视频 | 国产盗摄一区二区三区在线 | 99久久国产综合精品1 | 久久精品视频免费看 | 久久只精品99品免费久23小说 | 国产香蕉97碰碰久久人人九色 | 色播久久人人爽人人爽人人片av | 日韩久久无码免费毛片软件 | HEYZO无码综合国产精蜜臀 | 一二区免费视频 | 国产熟熟 | 99精品免费久久久久久久久日本 | 激情二区 | 日本免费一二三区中文 | 国内盗摄视频一区二区三区 | 樱桃视频高清免费观看在线 | 亚洲国产婷婷影院 | www.97.超碰.zyz.com| 欧美劲爆婷婷五月久久 | 在线成年人视频 | 亚洲日本欧美天堂在线手机版 | 五月激情网站 | 亚洲成年网站青青草原 | 亚洲香蕉视频综合在线 | 天天射寡妇射 | 日本道不卡 | 日日碰狠狠添天天爽 | 国产农村熟妇videos |